紫杉烷类药物引起的指甲改变：发生率、临床表现及转归

Taxane-induced nail changes: incidence, clinical presentation and outcome.

作者信息

Minisini A M, Tosti A, Sobrero A F, Mansutti M, Piraccini B M, Sacco C, Puglisi F

机构信息

Clinical Oncology, University of Udine, Udine, Italy.

出版信息

Ann Oncol. 2003 Feb;14(2):333-7. doi: 10.1093/annonc/mdg050.

DOI:10.1093/annonc/mdg050

PMID:12562663

Abstract

The clinical characteristics of nail changes in seven patients receiving taxane-containing chemotherapy are described. They include nail pigmentation, subungual hematoma, Beau's lines and onycholysis and subungual suppuration. The incidence of such changes (ranging from 0% to 44%) is reviewed from a Medline search of the literature.

摘要

本文描述了7例接受含紫杉烷化疗患者指甲改变的临床特征。这些改变包括指甲色素沉着、甲下血肿、博氏线、甲分离和甲下化脓。通过对医学文献数据库（Medline）检索文献，回顾了此类改变的发生率（范围为0%至44%）。