Kouri Vivian, Cartaya Judith, Rodríguez María E, Muné Mayra, Soto Yudira, Resik Sonia, Bravo Jose, Llop Alina
Departamento de Virología, Instituto de Medicina Tropical 'Pedro Kouri', Ciudad de la Habana, Cuba.
Mem Inst Oswaldo Cruz. 2002 Dec;97(8):1073-7. doi: 10.1590/s0074-02762002000800001. Epub 2003 Jan 20.
To determine the prevalence rates and serovar distribution of Chlamydia trachomatis cervical infections in Cuban women, two different groups were selected. Group I consisted of 60 human immunodeficiency virus (HIV-1) seropositive women from different regions of Cuba and group II of 60 randomly selected women HIV seronegative and apparently healthy. C. trachomatis was detected in cervical scrapes by mean of nested polymerase chain reaction (PCR) specific for major out membrane protein. The overall prevalence rate of C. trachomatis in cervical scrapes determined by nested PCR was 10% in group I and the estimated prevalence was 6.6% for group II; 83.3% of HIV seropositive women with C. trachomatis infection reported history of pelvic inflammatory disease followed by cervicitis (50%). The control group C. trachomatis-infected women referred a history of cervicitis in 75% of cases. Other reports in the latter group included infertility and pelvic inflamatory disease in 50%. The present study is the first report of C. trachomatis prevalence in Cuba. It showed that there was not significantly difference in the prevalence rate of C. trachomatis between both groups.
为确定古巴女性沙眼衣原体宫颈感染的患病率及血清型分布，选取了两组不同的女性。第一组由来自古巴不同地区的60名人类免疫缺陷病毒（HIV-1）血清阳性女性组成，第二组由60名随机选取的HIV血清阴性且表面健康的女性组成。通过针对主要外膜蛋白的巢式聚合酶链反应（PCR）检测宫颈刮片中的沙眼衣原体。通过巢式PCR确定的宫颈刮片中沙眼衣原体的总体患病率在第一组为10%，第二组估计患病率为6.6%；83.3%感染沙眼衣原体的HIV血清阳性女性报告有盆腔炎病史，其次是宫颈炎（50%）。对照组中感染沙眼衣原体的女性75%有宫颈炎病史。后一组中的其他报告包括50%有不孕和盆腔炎。本研究是古巴沙眼衣原体患病率的首次报告。结果显示两组之间沙眼衣原体的患病率没有显著差异。
