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Fibroblasts play a stimulatory role in keratinocyte proliferation but an inhibitory role in melanocyte growth and pigmentation in a skin equivalent system from skin type IV.

作者信息

Lee Dong-Youn, Lee Joo-Heung, Lee Eil-Soo, Cho Kwang-Hyun, Yang Jun-Mo

机构信息

Department of Dermatology, Sungkyunkwan University School of Medicine, Samsung Medical Center, Seoul, Republic of Korea.

出版信息

Arch Dermatol Res. 2003 Jan;294(10-11):444-6. doi: 10.1007/s00403-002-0359-2. Epub 2002 Nov 21.

DOI:10.1007/s00403-002-0359-2
PMID:12563542
Abstract
摘要

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Fibroblasts play a stimulatory role in keratinocyte proliferation but an inhibitory role in melanocyte growth and pigmentation in a skin equivalent system from skin type IV.在IV型皮肤的皮肤替代系统中，成纤维细胞对角质形成细胞的增殖起刺激作用，但对黑素细胞的生长和色素沉着起抑制作用。
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引用本文的文献

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Comparison of photodamage in non-pigmented and pigmented human skin equivalents exposed to repeated ultraviolet radiation to investigate the role of melanocytes in skin photoprotection.比较反复暴露于紫外线辐射下的无色素和有色素的人体皮肤等效物中的光损伤，以研究黑素细胞在皮肤光保护中的作用。
Front Med (Lausanne). 2024 Apr 18;11:1355799. doi: 10.3389/fmed.2024.1355799. eCollection 2024.
2
Race Does Not Predict Melanocyte Heterogeneous Responses to Dermal Fibroblast-Derived Mediators.种族无法预测黑素细胞对真皮成纤维细胞衍生介质的异质性反应。
PLoS One. 2015 Sep 29;10(9):e0139135. doi: 10.1371/journal.pone.0139135. eCollection 2015.