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[功能性鼻内镜鼻窦手术对黏液纤毛清除功能的影响]

[The effect of functional endoscopic sinus surgery on mucociliary clearance].

作者信息

Wang Y F, Ye F C, Wang M S

机构信息

Department of Otolaryngology, Anhui Provincial Hospital, Hefei 230001.

出版信息

Lin Chuang Er Bi Yan Hou Ke Za Zhi. 2000 Aug;14(8):339-41.

Abstract

OBJECTIVE

To explore the effect of functional endoscopic sinus surgery(FESS) on the mucociliary clearance of nasal mucosa.

METHOD

105 patients suffered from chronic sinusitis and undergone FESS from Jan. 1998 to Dec. 1998 were staged and analyzed according to the standard set up in Haikou in 1997. The nasal mucociliary transport rate (MTR) was measured by "saccharin" before, three months and six months after surgery.

RESULT

  1. The difference of the stages for chronic sinusitis affected directly the surgical result. 2. The difference of properties, limits and extents of pathological changes in sinuses was significantly associated with the MTR. The MTR showed a marked reduction in stage II-II, II-III and III. The MTR was increased after surgery. 3. The difference of the stages affected directly the recovery of MTR. The MTR in stage I-I, I-II, I-III and II-I recovered more quickly.

CONCLUSION

The MTR of nasal mucosa tended to recover after FESS. The study confirmed that the present staging system for chronic sinusitis was seasonable. We therefore propose the "saccharin" technique as a simple, safe, reliable and objective method of assessing the results of surgery.

摘要

目的

探讨功能性鼻内镜鼻窦手术(FESS)对鼻黏膜黏液纤毛清除功能的影响。

方法

对1998年1月至12月行FESS的105例慢性鼻窦炎患者,按1997年海口会议制定的标准进行分期并分析。术前、术后3个月及6个月采用“糖精法”测定鼻黏液纤毛传输率(MTR)。

结果

  1. 慢性鼻窦炎的分期差异直接影响手术效果。2. 鼻窦病变性质、范围及程度的差异与MTR显著相关。在Ⅱ-Ⅱ、Ⅱ-Ⅲ及Ⅲ期MTR明显降低。术后MTR升高。3. 分期差异直接影响MTR的恢复。Ⅰ-Ⅰ、Ⅰ-Ⅱ、Ⅰ-Ⅲ及Ⅱ-Ⅰ期MTR恢复较快。

结论

FESS术后鼻黏膜MTR有恢复趋势。本研究证实现行慢性鼻窦炎分期系统是适时的。因此我们推荐“糖精法”作为一种评估手术效果的简单、安全、可靠且客观的方法。

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