Elwany S, Hisham M, Gamaee R
Department of Otolaryngology, Alexandria Medical School, Alexandria, Egypt.
Eur Arch Otorhinolaryngol. 1998;255(10):511-4. doi: 10.1007/s004050050109.
The saccharin test was used to measure mucociliary clearance in 50 patients with symptoms of chronic sinusitis. Samples of the nasal mucosa were also examined under transmission electron microscopy before and after functional endoscopic sinus surgery (FESS). Before surgery, the mean saccharin clearance (ST) was 37.0 +/- 15.7 min, with nasal mucosa exhibiting ciliary loss as well as other ultrastructural changes. Three months after surgery, the mean ST had improved to 20.3 +/- 7.5 min and significant regeneration of cilia was observed. It was therefore concluded that FESS had successfully corrected mucociliary dysfunction in these patients.
使用糖精试验对50例慢性鼻窦炎患者的黏液纤毛清除功能进行测量。在功能性鼻内镜鼻窦手术（FESS）前后，还对鼻黏膜样本进行了透射电子显微镜检查。手术前，平均糖精清除时间（ST）为37.0±15.7分钟，鼻黏膜出现纤毛缺失以及其他超微结构改变。手术后三个月，平均ST改善至20.3±7.5分钟，观察到纤毛有明显再生。因此得出结论，FESS成功纠正了这些患者的黏液纤毛功能障碍。
