Ciccolo A, Centorrino T, Rossitto M, Fonti M T, Barbera A, De Jesi F
Università degli Studi di Messina Azienda Ospedaliera Universitaria Policlinico G. Martino UU.OO. di Chirurgia Il e Patologia Ano-Rettale.
G Chir. 2002 Aug-Sep;23(8-9):337-41.
The Authors report two cases of GIST and underline cytogenetic, clinic and prognostic aspects of this disease; they describe as well new histo-cyto-genetic data that identify as origin tissue interstitial cells of Cajal, by immunohistochemical and genetic tests. They also consider new diagnostic and therapeutic options based on surgical treatment. Finally controversial prognostic problems are discussed.
作者报告了两例胃肠道间质瘤（GIST）病例，并强调了该疾病的细胞遗传学、临床和预后方面；他们还描述了通过免疫组织化学和基因检测确定为起源组织是 Cajal 间质细胞的新组织细胞遗传学数据。他们还考虑了基于手术治疗的新诊断和治疗选择。最后讨论了有争议的预后问题。
