Ryeng Kathrine A, Larsen Stig, Arnemo Jon M
Norwegian School of Veterinary Science, Department of Arctic Veterinary Medicine, NO-9292 Tromsø, Norway.
J Zoo Wildl Med. 2002 Dec;33(4):397-400. doi: 10.1638/1042-7260(2002)033[0397:MKIRRT]2.0.CO;2.
Twelve reindeer (Rangifer tarandus tarandus) were immobilized by hand injection in indoor stalls with established optimal hand-injection doses of medetomidine-ketamine and then moved to outside paddocks where they were immobilized again with the same dose by dart. The reindeer in paddocks were immobilized a second time with a 50% higher dose, hereafter referred to as the optimal darting dose. Mean time to first sign of sedation was longer and mean induction time was significantly longer (55% and 79%, respectively) when the optimal hand-injection dose was dart injected versus hand injected. Mean time to first sign of sedation was not significantly shorter (although 21% shorter, numerically) but mean induction time was significantly shorter (30%) when animals were darted with the optimal darting dose versus darted with the optimal hand-injection dose. There were no significant differences in respiratory rate, rectal temperature, and relative arterial oxygen saturation in animals injected with different doses and by different routes. but there was a significantly lower heart rate in animals dart injected with the optimal darting dose versus dart injected with the optimal hand-injection dose. All animals responded at similar rates to atipamezole injection.
12只驯鹿（Rangifer tarandus tarandus）在室内畜栏中通过手动注射既定的美托咪定 - 氯胺酮最佳手动注射剂量进行麻醉，然后转移到室外围场，在那里用相同剂量的麻醉镖再次进行麻醉。围场中的驯鹿第二次用高50%的剂量进行麻醉，此后称为最佳麻醉镖剂量。与手动注射最佳手动注射剂量相比，当通过麻醉镖注射最佳手动注射剂量时，首次出现镇静迹象的平均时间更长，平均诱导时间显著更长（分别为55%和79%）。与用最佳手动注射剂量进行麻醉镖注射相比，当用最佳麻醉镖剂量对动物进行麻醉镖注射时，首次出现镇静迹象的平均时间虽未显著缩短（尽管在数值上短21%），但平均诱导时间显著缩短（30%）。不同剂量和不同途径注射的动物在呼吸频率、直肠温度和相对动脉血氧饱和度方面没有显著差异。但是，与用最佳手动注射剂量进行麻醉镖注射相比，用最佳麻醉镖剂量进行麻醉镖注射的动物心率显著更低。所有动物对阿替美唑注射的反应率相似。
