肾水通道蛋白：从分子到人类疾病
Renal aquaporin water channels: from molecules to human disease.
作者信息
Schrier Robert W, Cadnapaphornchai Melissa A
机构信息
Department of Medicine, University of Colorado School of Medicine, 4200 East Ninth Avenue, Box B178, Denver, CO 80262, USA.
出版信息
Prog Biophys Mol Biol. 2003 Feb;81(2):117-31. doi: 10.1016/s0079-6107(02)00049-4.
Abstract
Following the discovery of the aquaporin-1 water channel in 1991, molecular techniques have been developed to examine the roles of renal aquaporins-1, -2, -3, and -4 in disorders of water balance. This article reviews current knowledge regarding aquaporin function and dysfunction in water-losing and water-retaining states.
摘要
1991年水通道蛋白-1水通道被发现后，人们开发了分子技术来研究肾水通道蛋白-1、-2、-3和-4在水平衡紊乱中的作用。本文综述了关于水通道蛋白在失水性和潴留性状态下功能及功能障碍的当前知识。
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