Hermann H J, Ammon J, Winkel K z, Haubold U
Rofo. 1975 May;122(5):456-61. doi: 10.1055/s-0029-1230113.
Iodine 123 is a nearly "ideal" radionuclide for thyroid imaging. The production of Iodine 123 requires cyclotrons or accelerators. The production of multicurie amounts of Iodine 123 has been suggested through the use of high-energy accelerators (less than 60 MeV). Most of the methods for the production of Iodine 123 using a compact cyclotron result in contamination with f.e. Iodine 124 which reduces the spatial resolution af imagining procedures and increases the radiation dose to the patient. The radiation dose has been calculated for three methods of production. The various contamination with Iodine 124, Iodine 125, and Iodine 126 result in comparable radiation dose of Iodine 131, provided that the time between production and application is more than four half-live-times of Iodine 123.
碘123是用于甲状腺成像的近乎“理想”的放射性核素。碘123的生产需要回旋加速器或加速器。有人建议通过使用高能加速器(低于60兆电子伏特)来生产多居里量的碘123。使用紧凑型回旋加速器生产碘123的大多数方法都会导致诸如碘124等污染物的产生,这会降低成像程序的空间分辨率并增加患者的辐射剂量。已经针对三种生产方法计算了辐射剂量。如果生产和应用之间的时间超过碘123的四个半衰期,则碘124、碘125和碘126的各种污染物会导致与碘131相当的辐射剂量。