Xu L Q, Xiao D H, Zhou C H, Zhang X Q, Lan S G, Zhen X X, Zhang W L, Fu J P, Ye B, Dang H, Zhu X Z, Huang S L
Institute of Parasitic Diseases, Chinese Academy of Preventive Medicine, WHO Collaborating Center for Malaria, Schistosomiasis and Filariasis, Shanghai 20025.
Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi. 2001;19(5):294-7.
To study the relationship between cleanliness of children's hands and diminution of Ascaris lumbricoides infection.
Before the study all persons positive for ascaris eggs in the preliminary survey were treated with albendazole. Hand-washing habit before meal and after defecation was kept in children of experimental group, but not in the control group. Kato thick smear stool examination was done once every two months for one year to compare the new infection rates in children without ascaris infection in the two groups, and the reinfection rates in the cured negative cases were also compared between them in half a month after chemotherapy.
All the new infection rates as well as reinfection rates of each reexamination in the experimental group were significantly lower than that of the control group (P < 0.001). Reexamination one year later showed that the ascaris infection rate of the experimental group was 35.2%, reducing by 48.5% as compared with 68.3% before the operation of the project; while ascaris infection rate of the control group was 73.7%, increasing by 78.0% as compared with 41.4% before the operation of the project.
Washing hands with toilet soap to keep hands clean can significantly reduce ascaris infection rate.
研究儿童手部清洁与蛔虫感染率降低之间的关系。
研究前,对初筛蛔虫卵阳性者均给予阿苯达唑治疗。试验组儿童保持饭前便后洗手的习惯,对照组则不要求。一年中每两个月进行一次粪便加藤厚涂片检查,比较两组无蛔虫感染儿童的新感染率,化疗后半月还比较了两组治愈阴性病例的再感染率。
试验组各次复查的新感染率和再感染率均显著低于对照组(P<0.001)。一年后复查显示,试验组蛔虫感染率为35.2%,与项目实施前的68.3%相比降低了48.5%;而对照组蛔虫感染率为73.7%,与项目实施前的41.4%相比升高了78.0%。
用肥皂洗手保持手部清洁可显著降低蛔虫感染率。