[老年白内障患者超氧化物歧化酶及微量元素的研究]
[The study on superoxide dismutase and trace element in patients with senile cataract].
作者信息
Yang W, Yu W, Li Z
机构信息
Deparment of Ophthalmology, Guangzhou First Municipal People's Hospital, Guangzhou 510180, China.
出版信息
Yan Ke Xue Bao. 2000 Dec;16(4):246-8, 234.
PURPOSE
To investigate the relation of senile cataract with superoxide dismutase(SOD) and trace elements.
METHODS
Superoxide dismutase of red blood cells and trace elements(Cu, Zn, Ca, Fe) of serum in 61 patients with senile cataract and 121 normal persons were investigated.
RESULTS
The activity of superoxide dismutase in patients with senile cataract decrease dramatically in comparison with normal control, and there was no statistical difference about trace elements of Cu, Zn, Ca between senile cataract and control group. But Fe element in patients is higher than that of the normal group.
CONCLUSION
The results support the hypothesis that the formation of senile cataract is capable of antioxidative scavenger system of lens decreases with age.
目的
探讨老年性白内障与超氧化物歧化酶（SOD）及微量元素的关系。
方法
对61例老年性白内障患者和121例正常人的红细胞超氧化物歧化酶及血清微量元素（铜、锌、钙、铁）进行检测。
结果
老年性白内障患者超氧化物歧化酶活性较正常对照组显著降低，老年性白内障组与对照组在铜、锌、钙微量元素方面无统计学差异，但患者铁元素高于正常组。
结论
结果支持以下假说，即随着年龄增长晶状体抗氧化清除系统功能减退导致老年性白内障形成。
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