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[反义技术在眼科中的应用]

[The application of antisense technology in ophthalmology].

作者信息

Guo Y, Ge J

机构信息

Zhongshan Ophthalmic Center, Sun Yat-sen University of Medical Sciences, Guangzhou 510060, China.

出版信息

Yan Ke Xue Bao. 1998 Jun;14(2):108-15.

Abstract

The research of gene regulation become more and more important with the advancement of the technology of molecular biology and gene study. Antisense molecules can regulate and modify gene expression. By using antisense technology, antisense RNA or artificial antisense oligonucleotides can be made to inhibit or block the transcription and translation of genes. These molecules are highly specific in gene regulation. The application of antisense technology in ophthalmology is introduced briefly in the review. This may be helpful to the studies in ophthalmic research field.

摘要

随着分子生物学和基因研究技术的进步,基因调控的研究变得越来越重要。反义分子可以调节和修饰基因表达。通过使用反义技术,可以制备反义RNA或人工反义寡核苷酸来抑制或阻断基因的转录和翻译。这些分子在基因调控方面具有高度特异性。本文简要介绍了反义技术在眼科中的应用。这可能有助于眼科研究领域的研究。

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