Rao Angela, Carbone Anna, Chimirri Alba, De Clercq Erik, Monforte Anna Maria, Monforte Pietro, Pannecouque Christophe, Zappalà Maria
Dipartimento Farmaco-Chimico, Università di Messina, viale Annunziata 98168, Messina, Italy.
Farmaco. 2003 Feb;58(2):115-20. doi: 10.1016/s0014-827x(02)00024-1.
Several 1,3-thiazolidin-4-ones bearing a 2,6-dihalophenyl group at C-2 and a variously substituted phenyl ring at N-3 have been synthesized and tested as anti-HIV agents. The results of the in vitro tests showed that some of them proved to be effective inhibitors of HIV-1 replication.
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