Wu Xinlin, Li Junbiao, Mo Suilin, Liu Hongjian, Zhou Ying, Shen Weizeng
First Affiliated Hospital, Sun Yat-Sen University of Medical Sciences, Guangzhou 510080.
Zhong Yao Cai. 2002 Jan;25(1):72-5.
To investigate the ameliorative effect on chronic uric acid nephropathy (CUAN) by integrating western and traditional Chinese medicine (IWTCM).
The 136 CUAN patients were divided into two groups at random, the therapy group of 86 patients were treated by Chinese medicine and allopurinol, and the control group of 50 patients were treated only by allopurinol. The curative effect and the related index such as blood uric acid, renal function, urinary protein, microproteins, blood lipid and hyperviscosity were determined before and after being treated.
After three months treatment, the total effective rate in the therapy group (90.7%) was significantly higher (P < 0.01) than that of the control group (56%). The therapy group is also superior to the control group in improving renal function, lipid metabolism and hyperviscosity, decreasing blood uric acid, urinary protein, microproteins in evidence (P < 0.05, P < 0.01).
IWTCM can obviously improve the ameliorative effect on chronic uric acid nephropathy.
探讨中西医结合治疗对慢性尿酸肾病（CUAN）的改善作用。
将136例慢性尿酸肾病患者随机分为两组，治疗组86例采用中药联合别嘌醇治疗，对照组50例仅采用别嘌醇治疗。治疗前后测定疗效及血尿酸、肾功能、尿蛋白、微量蛋白、血脂和血液黏稠度等相关指标。
治疗3个月后，治疗组总有效率（90.7%）明显高于对照组（56%）（P<0.01）。治疗组在改善肾功能、脂质代谢和血液黏稠度、降低血尿酸、尿蛋白、微量蛋白方面也明显优于对照组（P<0.05，P<0.01）。
中西医结合治疗能明显提高对慢性尿酸肾病的改善作用。
