Morikawa Shigehiro, Inubushi Toshiro, Kurumi Yoshimasa, Naka Shigeyuki, Sato Koichiro, Tani Tohru, Haque Hasnine A, Tokuda Jun-ichi, Hata Nobuhiko
Molecular Neuroscience Research Center, Shiga University of Medical Science, Seta Tsukinowa-cho, Ohtsu, Shiga 520-2192, Japan.
Acad Radiol. 2003 Feb;10(2):180-8. doi: 10.1016/s1076-6332(03)80043-0.
The purpose of this study was to develop and test new assistive devices to aid in the performance of safe, easy, and accurate microwave thermocoagulation therapy guided by magnetic resonance (MR) imaging.
An open-configuration MR imager with an optical tracking system for image plane control and a microwave coagulator operating at 2.45 GHz were used. Liver tumors were percutaneously punctured under the guidance of MR images and ablated. Handpiece adapters were then prepared for the optical tracking system. An MR-compatible endoscopic system also was used. Navigation software was installed and customized. These devices were combined to provide near-real-time MR image-guided navigation during thermocoagulation therapy for liver tumors.
The handpiece adapters improved the flexibility of approaches for percutaneous puncture of tumors. The MR-compatible endoscope was used as a thoracoscope, and tumors just below the diaphragm were safely and easily punctured through the diaphragm. The customized navigation software displayed near-real-time MR images together with two reformatted images (on the same plane and on a perpendicular plane) from the registered high-resolution three-dimensional data, enabling accurate MR imaging navigation.
These new assistive devices made it easier to perform safe, easy, and accurate MR-guided thermocoagulation therapy of liver tumors.
本研究的目的是研发并测试新型辅助设备,以协助在磁共振(MR)成像引导下进行安全、简便且精确的微波热凝治疗。
使用一台具有用于图像平面控制的光学跟踪系统的开放式配置MR成像仪以及一台工作频率为2.45 GHz的微波凝固器。在MR图像引导下经皮穿刺肝脏肿瘤并进行消融。然后为光学跟踪系统准备手持适配器。还使用了一种MR兼容的内镜系统。安装并定制了导航软件。这些设备组合起来可在肝脏肿瘤热凝治疗期间提供近实时的MR图像引导导航。
手持适配器提高了经皮穿刺肿瘤方法的灵活性。MR兼容的内镜用作胸腔镜,可安全、轻松地经膈肌穿刺位于膈肌下方的肿瘤。定制的导航软件可显示近实时的MR图像以及来自已配准的高分辨率三维数据的两张重新格式化图像(在同一平面和垂直平面上),从而实现精确的MR成像导航。
这些新型辅助设备使在MR引导下对肝脏肿瘤进行安全、简便且精确的热凝治疗变得更加容易。