Taniguchi Masayuki, Nakano Hajime, Kuwahara Koichiro, Masuda Izuru, Okawa Yasuhiro, Miyazaki Hiroshi, Okoshi Hirofumi, Kaji Masanobu, Noguchi Yoshiko, Asukata Ichiro
Flight Crew Medical Service Department, Japan Airline, 3-6-8 Haneda-kuko, Ohta-ku, Tokyo 144-0041.
Intern Med. 2003 Jan;42(1):21-4. doi: 10.2169/internalmedicine.42.21.
The purpose of this study was to evaluate the prognostic and clinical significance of newly acquired complete right bundle branch block (CRBBB) in airline pilots.
This study included pilots with acquired CRBBB, identified from a group of over 2,700 Japan Airline pilots. When the pilots applied for employment, a past medical history, physical examination, electrocardiogram, and chest radiograph were obtained. The pilots with ECG abnormality including CRBBB were not included in the study because of hiring requirements.
Thirty-six pilots with CRBBB were identified between 1983 and 2002. All pilots with CRBBB were evaluated for the presence of ischemic heart disease by treadmill exercise testing, echocardiogram and exercise thallium scintigraphy. Twelve individuals underwent coronary angiography. The mean age of pilots was 44.4 +/- 5.8 years. The mean observation period was 10.9 +/- 5.7 years. For each of the 36 study subjects, Holter electrocardiogram and echocardiogram were obtained every 6 months after the CRBBB was detected. Exercise stress testing was performed every year. Exercise thallium scintigraphy was performed every 2 years to detect ischemic heart disease. During the observation period, two pilots stopped flying temporarily because of frequent ventricular premature beats and one pilot stopped flying permanentaly because of atrial fibrillation. During the follow-up period, no cardiovascular events were observed in pilots with CRBBB who had no underlying ischemic heart disease.
Acquired CRBBB does not confer a poor prognosis, particularly in young men working as a pilot if there is no evidence of ischemia on exercise stress testing, echocardiography and exercise thallium scintigraphy.
本研究旨在评估航空公司飞行员新出现的完全性右束支传导阻滞(CRBBB)的预后及临床意义。
本研究纳入了从2700多名日本航空公司飞行员中识别出的获得性CRBBB飞行员。飞行员入职时,获取了既往病史、体格检查、心电图和胸部X光片。因招聘要求,包括CRBBB在内的心电图异常的飞行员未纳入本研究。
1983年至2002年期间共识别出36名患有CRBBB的飞行员。所有患有CRBBB的飞行员均通过平板运动试验、超声心动图和运动铊闪烁显像评估是否存在缺血性心脏病。12人接受了冠状动脉造影。飞行员的平均年龄为44.4±5.8岁。平均观察期为10.9±5.7年。对于36名研究对象中的每一位,在检测到CRBBB后每6个月进行一次动态心电图和超声心动图检查。每年进行运动应激试验。每2年进行一次运动铊闪烁显像以检测缺血性心脏病。在观察期内,两名飞行员因频发室性早搏暂时停飞,一名飞行员因心房颤动永久停飞。在随访期内,无潜在缺血性心脏病的CRBBB飞行员未观察到心血管事件。
获得性CRBBB预后并不差,尤其是对于年轻男性飞行员,如果运动应激试验、超声心动图和运动铊闪烁显像均无缺血证据。