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核孔复合体的中央通道真的是大分子运输的唯一通道吗?

Is the central channel of nuclear pore complex really the exclusive gateway for macromolecular transport?

作者信息

Prachar J

机构信息

Cancer Research Institute, Bratislava, Slovakia.

出版信息

Neoplasma. 2002;49(6):368-78.

Abstract

Examination of many nuclear pore complexes revealed in some of them very thin filaments presumably RNA with accompanying proteins, directing from inner nucleus to the edge of the complex. On one representative micrograph it is shown that this strand continues in the same direction through central part of the complex most probably through the peripheral channel. Next route of the strand is through the tunnel of a hollow rod - subunit of the cytoplasmic ring.

摘要

对许多核孔复合体的检查发现,其中一些含有非常细的细丝,推测是带有相关蛋白质的RNA,从细胞核内部延伸至复合体边缘。在一张代表性的显微照片上显示,这条链以相同方向穿过复合体的中心部分,很可能是通过外围通道。这条链的下一步路径是穿过空心杆(细胞质环的亚基)的通道。

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