Kreder Hans J, Grosso Paul, Williams Jack I, Jaglal Susan, Axcell Tami, Wal Eugene K, Stephen David J G
Musculoskeletal Health Status Working Group Institute for Clinical Evaluative Sciences (ICES), University of Toronto, Toronto, Ont.
Can J Surg. 2003 Feb;46(1):15-22.
Because of rationing of the limited pool of health care resources, access to total knee arthroplasty (TKA) is limited, but investigation of variables that predict complications, length of hospital stay, cost and outcomes of TKA may allow us to optimize the available resources. The objective of this study was to examine the effect of various factors on complication rates after TKA in patients managed in Ontario.
Patients who had undergone an elective TKA between 1993 and 1996, as captured in the Canadian Institute for Health Information (CIHI) database, formed the study cohort. The CIHI dataset was used to obtain information regarding in-hospital complications, hospital length of stay, revision rates, infection rates and mortality. Generalized estimating linear or logistic regression equations were used to model outcomes as a function of age, gender, comorbidity, diagnosis and provider volume.
During the study period, 14,352 patients in Ontario underwent TKA. Mortality at 3 months was associated with patient age, gender and comorbidity. There was no association between provider volume and mortality or the infection rate. Higher revision rates at 1 and 3 years were significantly associated with lower patient age and low hospital volume (p < 0.05). Hospitals in which fewer than 48 TKA procedures were done per year (< 40th percentile) had 2.2-fold greater 1-year revision rates than hospitals performing more than 113 TKAs annually (> 80th percentile). Complications during admission were associated with increased patient age and comorbidity, and higher hospital volume. Longer hospital stay was associated with female gender, increasing patient comorbidity and age, and lower provider volume. Surgeons who performed fewer than 14 TKAs annually (< 40th percentile) kept patients in hospital an average of 1.4 days longer than surgeons performing more than 42 TKAs annually (> 80th percentile).
Patient variables significantly affect the rate of complications. Age, sex and comorbidity were significant predictors of complications, length of hospital stay and mortality after TKA. Although low surgeon volume was related to longer hospital stay, there was no association between surgeon volume and complication rates. The increased early revision rate for low-volume hospitals demands further study.
由于医疗保健资源有限,全膝关节置换术(TKA)的可及性受限,但对预测TKA并发症、住院时间、成本及结果的变量进行研究,可能会使我们优化现有资源。本研究的目的是探讨安大略省接受治疗的患者中各种因素对TKA术后并发症发生率的影响。
以加拿大卫生信息研究所(CIHI)数据库中记录的1993年至1996年间接受择期TKA的患者组成研究队列。CIHI数据集用于获取有关住院并发症、住院时间、翻修率、感染率和死亡率的信息。使用广义估计线性或逻辑回归方程将结果建模为年龄、性别、合并症、诊断和医疗服务提供者手术量的函数。
在研究期间,安大略省有14352名患者接受了TKA。3个月时的死亡率与患者年龄、性别和合并症有关。医疗服务提供者手术量与死亡率或感染率之间无关联。1年和3年时较高的翻修率与较低的患者年龄和低手术量医院显著相关(p<0.05)。每年进行少于48例TKA手术的医院(<第40百分位数)的1年翻修率比每年进行超过113例TKA手术的医院(>第80百分位数)高2.2倍。住院期间的并发症与患者年龄增加、合并症以及更高的手术量医院有关。住院时间较长与女性性别、患者合并症和年龄增加以及较低的医疗服务提供者手术量有关。每年进行少于14例TKA手术的外科医生(<第40百分位数)让患者住院的时间平均比每年进行超过42例TKA手术的外科医生(>第80百分位数)长1.4天。
患者变量显著影响并发症发生率。年龄、性别和合并症是TKA术后并发症、住院时间和死亡率的重要预测因素。虽然外科医生手术量低与住院时间长有关,但外科医生手术量与并发症发生率之间无关联。低手术量医院早期翻修率增加需要进一步研究。