Schmidt-Hieber W, Strecker E P, Brobmann G F, Barth K, Birg W, Schmidt H A
Acta Hepatogastroenterol (Stuttg). 1976 Feb;23(1):47-52.
Digitalis glycosides have the well known positive inotropic effect on the heart. Their effect on extracardiac vascular smooth muscle receives increasing attention. In experimental animals a significant decrease in mesenteric blood flow and an increase in mesenteric vascular resistance could be shown. Angiography of main mesenteric arteries, smaller arteries, and arterioles reveal typical vasoconstriction. Angiomorphometric measurements show good correlation between the decrease in vascular diameter and the increase in vascular resistance.
洋地黄糖苷对心脏具有众所周知的正性肌力作用。它们对心脏外血管平滑肌的作用受到越来越多的关注。在实验动物中,可以观察到肠系膜血流量显著减少,肠系膜血管阻力增加。对肠系膜主要动脉、较小动脉和小动脉进行血管造影显示典型的血管收缩。血管形态测量表明血管直径减小与血管阻力增加之间具有良好的相关性。