Nabika Shinya, Oki Shuichi, Migita Keisuke, Isobe Naoyuki, Okazaki Takahito, Watanabe Yosuke
Department of Neurosurgery, Hiroshima City Asa Hospital, Hiroshima, Japan.
Hiroshima J Med Sci. 2002 Dec;51(4):93-6.
We present a case of ruptured distal posterior inferior cerebellar artery (PICA) aneurysm, and review the literature and discuss the treatment strategy. A 77-year-old woman presented with the sudden onset of severe headache, nausea and vomiting. Computed tomography revealed an intraventricular hemorrhage, predominantly in the fourth ventricle and hydrocephalus with a thin subarachinoid hemorrhage (SAH). Angiography revealed an aneurysm arising at the turning point of the vessel, from the telovelotonsillar segment of the right PICA. On the 17th day after the onset, repeated angiography revealed a smaller aneurysm than the one detected on the first day at the same place and with no spasm. On the 22nd day, the aneurysm was proved to be partially thrombosed and was safely clipped via a right lateral suboccipital approach. SAH with a fourth ventricular hemorrhage or an isolated fourth ventricle hemorrhage should raise the suspicion of a distal PICA aneurysm. Aneurysms of the distal PICA have often been reported to arise at a turning point of the artery rather than at a junction of the vessel. It is suggested that the pathogenesis could be hemodynamic stress that has developed due to embryological factors. Distal PICA aneurysms have often gone detected in many previous cases because of thrombosis inside the aneurysms. Thus, particularly in the case of intentionally delayed surgery, we recommend repeated angiography under various conditions to identify how the aneurysm develops just before surgery.
我们报告一例小脑后下动脉(PICA)远端动脉瘤破裂的病例,并回顾相关文献并讨论治疗策略。一名77岁女性突发严重头痛、恶心和呕吐。计算机断层扫描显示脑室内出血,主要位于第四脑室,并伴有脑积水及少量蛛网膜下腔出血(SAH)。血管造影显示动脉瘤起源于血管的转折点,位于右侧PICA的终池扁桃体段。发病后第17天,重复血管造影显示动脉瘤较第一天在同一位置发现的更小,且无痉挛。第22天,证实动脉瘤部分血栓形成,通过右侧枕下外侧入路安全夹闭。伴有第四脑室出血的SAH或孤立的第四脑室出血应怀疑为PICA远端动脉瘤。PICA远端动脉瘤常报道起源于动脉的转折点而非血管的交界处。提示其发病机制可能是由于胚胎学因素导致的血流动力学应激。由于动脉瘤内血栓形成,PICA远端动脉瘤在许多既往病例中常未被发现。因此,特别是在有意延迟手术的情况下,我们建议在各种条件下重复血管造影,以确定手术前动脉瘤的发展情况。