[Cytoarchitechtonics of the lymphoid tissue associated with the cecum wall in man in adolescence].

Cytoarchitectonics of lymphoid nodules (including apex, central zone and basis) and mucosal lamina propria cellular composition were studied in histological sections of cecum wall (dome area) in adolescents aged 12-16 years. It is shown that within lymphoid nodules the lowest cell concentration per unit section area is found in the apical area. The latter is also a region containing significant number of plasma cells. Apparent rarefication of cells in the central part of lymphoid nodules, high content of eosinophils, plasma cells and macrophages, increased cell destruction in lamina propria of cecal mucosa collectively indicate the changes in barrier function in intestinal wall of adolescents. Timing of these changes coincides with hormonal reorganization of the whole organism.