Lerdthusnee Kriangkrai, Khlaimanee Nittaya, Monkanna Taweesak, Mungviriya Siriporn, Leepitakrat Warisa, Debboun Mustapha, Coleman Russell E
Department of Entomology, US Army Medical Component, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand.
J Med Entomol. 2003 Jan;40(1):64-7. doi: 10.1603/0022-2585-40.1.64.
We developed a rapid and economical in vitro procedure with which to evaluate the efficacy of candidate repellents against chiggers. The procedure requires only 5 min and a small number of chiggers to obtain a valid estimate of the median effective dose. We used this procedure to evaluate the repellent activity of 11 compounds against the chigger, Leptotrombidium imphalum Vercammen-Grandjean and Langston. Median effective doses were determined for 10 of the 11 compounds. DM-165-2 (N,N-diethyl-3-flurobenzamide) was the only compound that was significantly more effective than deet.
我们开发了一种快速且经济的体外实验方法，用于评估候选驱避剂对恙螨的效果。该方法仅需5分钟和少量恙螨，就能有效估算出半数有效剂量。我们用此方法评估了11种化合物对恙螨（冲绳恙螨）的驱避活性。测定了其中10种化合物的半数有效剂量。DM - 165 - 2（N,N - 二乙基 - 3 - 氟苯甲酰胺）是唯一一种比避蚊胺显著更有效的化合物。
