Abel Michael P, Murphy Frederick T, Enzenauer Raymond J, Enzenauer Robert W
Department of Medicine, Brooke Army Medical Center, Fort Sam Houston, Texas, USA.
Binocul Vis Strabismus Q. 2003;18(1):29-30.
INO in SLE is uncommon, affecting < 5% of hospitalized SLE patients. A MEDLINE search 1966-2001 revealed only 22 reported cases. INO also rarely presents with diplopia. We report such a case.
A 35 year old woman with long standing SLE developed the abrupt onset of diplopia, vertigo and ataxia. Physical examination was remarkable only for the neurologic examination with a left INO and abnormal cerebellar testing. Treatment with corticosteroids and intravenous cyclophosphamide resulted in resolution of her cerebellar and ocular symptoms.
系统性红斑狼疮(SLE)中的核间性眼肌麻痹(INO)并不常见,在住院的SLE患者中发生率低于5%。对1966年至2001年期间的医学文献数据库(MEDLINE)进行检索,仅发现22例相关报道。INO也很少表现为复视。我们报告这样一例病例。
一名患有长期SLE的35岁女性突然出现复视、眩晕和共济失调。体格检查仅在神经系统检查时发现明显异常,表现为左侧INO及小脑检查异常。使用皮质类固醇和静脉注射环磷酰胺治疗后,其小脑和眼部症状得以缓解。