Morandini Piero, Salamini Francesco
Department of Biology, University of Milan, via Celoria 26, 20133 Milan, Italy.
Trends Plant Sci. 2003 Feb;8(2):70-5. doi: 10.1016/S1360-1385(02)00027-4.
Plant metabolic engineering is lagging behind other kinds of genetic manipulation of plants. Creating metabolic pathways or improving their yields requires a better understanding of plant metabolism and of its regulation. Metabolic Control Analysis provides an interpretation of experimental failures and a guide for manipulators. It suggests also that there might be intrinsic limits to raising yields in already abundant products. At present, these limits can be dealt with more effectively by plant breeding.
植物代谢工程落后于植物的其他基因操作类型。创建代谢途径或提高其产量需要更好地了解植物代谢及其调控。代谢控制分析为实验失败提供了解释,并为操纵者提供了指导。它还表明,提高已丰富产品的产量可能存在内在限制。目前,通过植物育种可以更有效地应对这些限制。