HIV-1感染患者治疗中断对健康相关生活质量的影响。
The impact on health-related quality of life of treatment interruptions in HIV-1-infected patients.
作者信息
Krentz Hartmut B, Gill M John
机构信息
Department of Anthropology, University of Calgary, Alberta, Canada.
出版信息
AIDS. 2003 Mar 7;17(4):631-3. doi: 10.1097/00002030-200303070-00022.
To examine health-related quality of life (HRQOL) before, during and after treatment interruptions (TI) in antiretroviral therapy, we analysed results from Medical Outcomes Study HIV health surveys on 50 HIV-1-infected patients. HRQOL scores decreased during a TI but increased after re-initiating treatment, although scores remained lower than those preceding the TI. The reasons for a TI differentially affected HRQOL. The findings suggest that TI should be based on medical decisions and not used to increase HRQOL.
为了研究抗逆转录病毒治疗期间治疗中断前后的健康相关生活质量（HRQOL），我们分析了50名HIV-1感染患者的医学结局研究HIV健康调查结果。治疗中断期间HRQOL评分下降，但重新开始治疗后升高，尽管评分仍低于治疗中断前。治疗中断的原因对HRQOL有不同影响。研究结果表明，治疗中断应基于医学决策，而不应被用于提高HRQOL。
Zotero 插件