Gordon M Y, Douglas I D, Clink H M, Pickering B M
Br J Haematol. 1976 Apr;32(4):537-42. doi: 10.1111/j.1365-2141.1976.tb00957.x.
The colony forming ability of bone marrow cells from 110 haematologically normal patients was investigated by their growth in semi-solid agar in intraperitoneal diffusion chambers. Marrow aspirated from the sternum showed a consistently higher colony yield than that from the iliac crest. Study of site variation in the individual was possible in donors for bone marrow transplantation. In each of four cases, sternal marrow produced more colonies than any other site. Examination of smears made from the aspirated samples suggested that the difference in yield was not due to varying dilution by peripheral blood on aspiration from different sites. It is concluded, therefore, that the incidence of colony precursor cells is not uniform throughout the active marrow.
通过在腹腔扩散小室的半固体琼脂中培养，研究了110例血液学正常患者骨髓细胞的集落形成能力。从胸骨抽取的骨髓显示出的集落产量始终高于从髂嵴抽取的骨髓。对于骨髓移植供体，可以研究个体的取材部位差异。在4例患者中，胸骨骨髓产生的集落均多于其他任何部位。对抽取样本制作的涂片进行检查表明，产量差异并非由于从不同部位抽取时外周血稀释程度不同所致。因此得出结论，集落前体细胞在整个活跃骨髓中的发生率并不一致。
