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[肺转移瘤的外科治疗]

[Surgery of lung metastasis].

作者信息

Delgado Muñoz M D, Antón-Pacheco J L, Matute J A, Cuadros J, Aguado P, Vivanco J L, Berchi F J

机构信息

Servicio de Cirugía Pediátrica, Hospital Universitario Doce de Octubre, Madrid.

出版信息

Cir Pediatr. 2000 Jan;13(1):7-10.

Abstract

INTRODUCTION

The 30-40% of the oncologic patients have pulmonary metastases. Lung can be the only organ affected. In selected patients, exeresis of the pulmonary nodules can mean their healing.

MATERIAL AND METHODS

Between 1982-1997, twenty two patients presented metastases, 13 could be operated and 16 thoracotomies were done. There were 53% boys and 47% girls whose ages ranged from 3 to 15 years. We have considered: pulmonary tumour location, disease free interval, number of metastases, surgical technique and incomplete pulmonary tumour resection.

RESULTS

Primary tumours were: Wilms tumours 23%, bone tumours 67% (Ewing and osteosarcoma). Disease free interval was < 2 years in 8 patients (61%) and > 2 years in 39%. X-Ray and CT were performed in every case and 66% presented a solitary nodule. Surgical techniques were: metastasectomy in two cases (12%), wedge resection in 8 (50%) and lobectomy in six cases (38%). We made thoracoscopy in two patients. There weren't postoperatory mortality but the patients with tumorectomy had an incomplete surgical resection. The overall survival is 54 percent and the 5 years survival is 23 percent (3 patients).

CONCLUSIONS

The patients with a DFI < 2 years have a survival of 25% compared with 100% for patients who have a DFI > 2 years. The pulmonary resection in selected patients can offer better survival. We can use the thoracoscopy in same selected patients.

摘要

引言

30% - 40%的肿瘤患者有肺转移。肺可能是唯一受影响的器官。在特定患者中,切除肺结节可能意味着治愈。

材料与方法

1982年至1997年间,22例患者出现转移,13例可进行手术,共进行了16次开胸手术。患者中男孩占53%,女孩占47%,年龄在3至15岁之间。我们考虑了:肺肿瘤位置、无病间期、转移灶数量、手术技术以及肺肿瘤切除不完全情况。

结果

原发肿瘤为:肾母细胞瘤占23%,骨肿瘤占67%(尤因肉瘤和骨肉瘤)。8例患者(61%)的无病间期<2年,39%的患者>2年。所有病例均进行了X线和CT检查,66%表现为单个结节。手术技术包括:2例(12%)进行了转移灶切除术,8例(50%)进行了楔形切除术,6例(38%)进行了肺叶切除术。我们对2例患者进行了胸腔镜检查。无术后死亡病例,但肿瘤切除术患者手术切除不完全。总生存率为54%,5年生存率为23%(3例患者)。

结论

无病间期<2年的患者生存率为25%,而无病间期>2年的患者生存率为100%。对特定患者进行肺切除术可提高生存率。我们可在部分特定患者中使用胸腔镜检查。

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