Lecendreux Michel, Konofal Eric
Service de psychopathologie de l'enfant et de l'adolescent Hôpital Robert-Debré 75019 Paris.
Rev Prat. 2002 Nov 15;52(18):2002-4.
Inattention, impulsiveness and hyperactivity are the main clinical features that characterise the attention deficit hyperactivity disorder (ADHD). Children with ADHD essentially present with diurnal manifestations but studies have recently shown a link between sleep and daytime symptoms. ADHD children could present sleep problems such as agitated sleep, sleep-onset difficulties, low arousal threshold during the night. Such sleep difficulties have been shown to occur more frequently in children with severe diurnal ADHD symptoms. Sleep studies using polysomnography have been performed in children with ADHD. Abnormalities during sleep such as increased motricity could be responsible for hypovigilance as measured using multiple sleep latency tests. Prevalence and physiopathology of sleep disorders including awakening mechanisms (micro-arousals, arousal threshold) from sleep yet need to be clarified in ADHD children. Understanding the mechanisms governing the sleep-wake balance seems essential for the comprehension of ADHD. Excessive nocturnal motricity could be the expression of a monoaminergic dysfunctioning previously reported in ADHD and could lead to new therapeutic gateways as well as hypovigilance.
注意力不集中、冲动和多动是注意力缺陷多动障碍(ADHD)的主要临床特征。患有ADHD的儿童主要表现为日间症状,但最近的研究表明睡眠与日间症状之间存在联系。患有ADHD的儿童可能会出现睡眠问题,如睡眠不安、入睡困难、夜间唤醒阈值低。这种睡眠困难在患有严重日间ADHD症状的儿童中更为常见。已对患有ADHD的儿童进行了使用多导睡眠图的睡眠研究。睡眠期间的异常,如运动增加,可能是使用多次睡眠潜伏期测试测量的警觉性降低的原因。包括从睡眠中唤醒机制(微觉醒、唤醒阈值)在内的睡眠障碍的患病率和病理生理学在患有ADHD的儿童中仍有待阐明。了解控制睡眠-觉醒平衡的机制似乎对于理解ADHD至关重要。夜间运动过多可能是先前在ADHD中报道的单胺能功能障碍的表现,并可能导致新的治疗途径以及警觉性降低。