Markovits D, Schapira D, Wiener A, Nahir A M
The B. Shine Department of Rheumatology, Rambam Medical Center, Haifa, 31096 Israel.
Clin Rheumatol. 2003 Feb;22(1):53-5. doi: 10.1007/s10067-002-0639-4.
We report a young male with recent onset of rheumatoid arthritis (RA) in whom the remarkable severity of the disease led to additional investigations. The only significant finding was mediastinal lymphadenopathy, without lung involvement. Biopsy of the mediastinal lymph node revealed pathological findings typical of silicosis. To our knowledge, this is the first report of silicosis apparent solely in the mediastinal lymph node of an RA patient. This suggests that lung involvement is not crucial for the development of silica-related arthritis.
我们报告了一名近期发病的类风湿关节炎(RA)青年男性患者,其病情严重程度显著,因此进行了进一步检查。唯一重要的发现是纵隔淋巴结肿大,无肺部受累。纵隔淋巴结活检显示出矽肺的典型病理表现。据我们所知,这是首例仅在RA患者纵隔淋巴结中出现明显矽肺的报告。这表明肺部受累对于硅相关关节炎的发展并非至关重要。