Bareła Anna D, Chazan Ryszarda
Katedry i Kliniki Chorób Wewnetrznych, Pneumonologii i Alergologii, Akademii Medycznej w Warszawie.
Wiad Lek. 2002;55(9-10):575-83.
The association of gastroesophageal reflux (GER) and respiratory symptoms has been investigated for a long time. The results of large number of studies are often conflicting. It seems, however, that with present knowledge an agreement concerning causal relationship between GER and asthma is possible to achieve. This article is to clarify available information related to the subject. It presents current views on pathogenesis of GER, its extra esophageal manifestations, suggested mechanisms linking reflux and respiratory symptoms. We analyzed diagnostic methods used when reflux is suspected as a cause of asthma exacerbations. The treatment recommended in such cases and its efficacy is discussed. Other diseases of the respiratory system connected with GER are also presented.
胃食管反流(GER)与呼吸道症状之间的关联已被研究了很长时间。大量研究的结果往往相互矛盾。然而,就目前的认知而言,关于GER与哮喘之间的因果关系达成共识是有可能的。本文旨在阐明与该主题相关的现有信息。它介绍了GER发病机制、其食管外表现、反流与呼吸道症状之间潜在机制的当前观点。我们分析了怀疑反流是哮喘发作原因时所使用的诊断方法。讨论了此类情况下推荐的治疗方法及其疗效。还介绍了与GER相关的其他呼吸系统疾病。