Flannery B A, Poole S A, Gallop R J, Volpicelli J R
Center for Interdisciplinary Substance Abuse Research, RTI International, P.O. Box 12194, 3040 Cornwallis Road-Hobbs 124, Research Triangle Park, North Carolina 27709-2194, USA.
J Stud Alcohol. 2003 Jan;64(1):120-6. doi: 10.15288/jsa.2003.64.120.
The purpose of this investigation was to examine the utility of thee craving instruments to predict drinking during treatment. The three assessments used were the Penn Alcohol Craving Scale (PACS), the Alcohol Urge Questionnaire (AUQ) and Items 1-6 of the Obsessive subscale (OBS) of the Obsessive Compulsive Drinking Scale (OCDS).
The three instruments were administered during the course of a 9-month, double-blind, placebo-controlled trial of 100 mg/day of naltrexone, and a manual-based psychosocial intervention using the BRENDA manual conducted at the University of Pennsylvania's Treatment Research Center. Participants (133 men and 50 women at the initiation of the study) used these instruments to self-report craving on a weekly or biweekly basis. The weekly number of drinks was reported using the Timeline Followback interview. The data were analyzed with generalized estimating equations using craving scores at 1 week as the independent variable and number of drinks in the subsequent treatment week as the dependent variable.
Each of the three scales predicted drinking during the subsequent treatment week. The PACS was the strongest predictor followed closely by the OBS and then the AUQ. Most important, craving as measured by the three scales was a stronger predictor of subsequent drinking than was drinking during the prior treatment week.
Craving assessment provides a useful means of predicting drinking during treatment. Such information would be helpful in designing clinical trials and for many treatment modalities.
本调查旨在检验这些渴求量表在预测治疗期间饮酒情况方面的效用。所使用的三项评估分别是宾夕法尼亚酒精渴求量表(PACS)、酒精冲动问卷(AUQ)以及强迫性饮酒量表(OCDS)的强迫观念分量表(OBS)中的第1 - 6项。
在一项为期9个月、双盲、安慰剂对照试验中,对100毫克/天的纳曲酮以及在宾夕法尼亚大学治疗研究中心进行的基于手册的社会心理干预(使用BRENDA手册)过程中使用这三项量表。参与者(研究开始时133名男性和50名女性)每周或每两周使用这些量表自我报告渴求情况。使用时间线回溯访谈报告每周饮酒量。以第1周的渴求分数作为自变量,后续治疗周的饮酒量作为因变量,采用广义估计方程对数据进行分析。
这三项量表中的每一项都能预测后续治疗周的饮酒情况。PACS是最强的预测指标,其次是OBS,然后是AUQ。最重要的是,与前一治疗周的饮酒情况相比,用这三项量表测量的渴求对后续饮酒情况的预测更强。
渴求评估为预测治疗期间的饮酒情况提供了一种有用的方法。此类信息有助于设计临床试验以及多种治疗方式。