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厌食症的病理生理学

Pathophysiology of anorexia.

作者信息

Morley John E

机构信息

Division of Geriatric Medicine, St. Louis University School of Medicine, 1402 South Grand Boulevard, M238, St. Louis, MO 63104, USA.

出版信息

Clin Geriatr Med. 2002 Nov;18(4):661-73, v. doi: 10.1016/s0749-0690(02)00047-2.

DOI:10.1016/s0749-0690(02)00047-2
PMID:12608495
Abstract

A physiologic decline in food intake occurs with advancing age. The physiologic anorexia of aging and its associated weight loss predispose older persons to develop protein-energy malnutrition. In older persons a variety of social and psychologic factors, diseases, and medications can aggravate the physiologic anorexia and lead to severe weight loss. Many of these factors are amenable to treatment, resulting in a reversal of the underlying malnutrition. This article first reviews the physiologic factors responsible for anorexia in older persons. It then reviews the major pathologic processes responsible for producing protein-energy malnutrition in older persons.

摘要

随着年龄的增长,食物摄入量会出现生理性下降。衰老导致的生理性厌食及其相关的体重减轻使老年人易患蛋白质 - 能量营养不良。在老年人中,多种社会和心理因素、疾病及药物会加重生理性厌食并导致严重体重减轻。其中许多因素是可以治疗的,从而扭转潜在的营养不良状况。本文首先回顾导致老年人厌食的生理因素。然后回顾导致老年人发生蛋白质 - 能量营养不良的主要病理过程。

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2
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