Piccart Martine, Dochy Emmanuelle, Cardoso Fatima
Unité de chimiothérapie, Institut Jules-Bordet, 1, rue Heger-Bordet, 1000 Bruxelles, Belgique.
Bull Cancer. 2003 Jan;90(1):46-52.
During the last decade, except for breast cancer, few "solid" tumours have benefited from significant progress in systemic treatment able to reduce the progression of metastases in advanced disease or to eradicate possible micro-metastases in the adjuvant situation. This review aims to guide the reader along the paths of the progress made in hormonotherapy, chemotherapy and targeted molecular therapy. For each category, the authors will attempt to estimate the impact of the therapeutic advances upon day-to-day clinical practice.
在过去十年中,除乳腺癌外,几乎没有“实体”肿瘤从全身治疗的显著进展中获益,这些进展能够减少晚期疾病中转移灶的进展或根除辅助治疗情况下可能存在的微转移灶。本综述旨在引导读者了解激素治疗、化疗和靶向分子治疗所取得的进展。对于每一类治疗,作者将尝试评估治疗进展对日常临床实践的影响。