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抑素对表皮细胞周期的调控。

Chalone regulation of the epidermal cell cycle.

作者信息

Thornley A L, Laurence E B

出版信息

Experientia. 1975 Sep 15;31(9):1024-6. doi: 10.1007/BF02326937.

DOI:10.1007/BF02326937
PMID:126173
Abstract

Purified epidermal G2 chalone does not inhibit DNA synthesis or influx of S-phase cells and is therefore cell cycle phase-specific, inhibiting only the flow of cells into M-phase.

摘要

纯化的表皮G2抑素并不抑制DNA合成或S期细胞的流入,因此具有细胞周期阶段特异性,仅抑制细胞进入M期的进程。

相似文献

1
Chalone regulation of the epidermal cell cycle.抑素对表皮细胞周期的调控。
Experientia. 1975 Sep 15;31(9):1024-6. doi: 10.1007/BF02326937.
2
Epidermal chalone: cell cycle specificity of two epidermal growth inhibitors.
Natl Cancer Inst Monogr. 1973 Jul;38:71-6.
3
Inhibition of cell proliferation in the livers of hepatectomized rats by a rabbit hepatic chalone.兔肝抑素对肝切除大鼠肝脏细胞增殖的抑制作用
Proc Natl Acad Sci U S A. 1974 May;71(5):1763-6. doi: 10.1073/pnas.71.5.1763.
4
Epidermal chalone and inhibition of DNA synthesis.
Natl Cancer Inst Monogr. 1973 Jul;38:93-8.
5
[Purification of epidermal G2-chalone using immunoaffinity chromatography].[利用免疫亲和层析法纯化表皮G2抑素]
Biull Eksp Biol Med. 1983 Aug;96(8):71-3.
6
Epidermal chalone and cyclic AMP: an in vivo study.表皮抑素与环磷酸腺苷:一项体内研究。
J Invest Dermatol. 1975 Jan;64(1):14-8. doi: 10.1111/1523-1747.ep12540874.
7
Recovery kinetics of epidermal cell proliferation after two intraperitoneal injections of epidermal extracts (chalone).两次腹腔注射表皮提取物(抑素)后表皮细胞增殖的恢复动力学
Virchows Arch B Cell Pathol Incl Mol Pathol. 1983;44(2):201-7. doi: 10.1007/BF02890170.
8
Effect of mechanical stimulation on cell proliferation in mouse epidermis and on growth regulation by endogenous factors (chalones).
Cell Tissue Kinet. 1976 Sep;9(5):445-57. doi: 10.1111/j.1365-2184.1976.tb01295.x.
9
Epidermal chalone--past to present concept.表皮抑素——从过去到现在的概念
J Invest Dermatol. 1975 Jul;65(1):67-70. doi: 10.1111/1523-1747.ep12598049.
10
Direct evidence of two tissue-specific chalone-like factors regulating mitosis and DNA synthesis in mouse epidermis.两种组织特异性类抑素因子调节小鼠表皮有丝分裂和DNA合成的直接证据。
Hoppe Seylers Z Physiol Chem. 1971 Sep;352(9):1273-4.

本文引用的文献

1
Extraction, purification and preliminary characterisation of the epidermal chalone: A tissue specific mitotic inhibitor obtained from vertebrate skin.表皮抑素的提取、纯化及初步特性分析:一种从脊椎动物皮肤中获得的组织特异性有丝分裂抑制剂。
Eur J Biochem. 1968 Jul;5(2):191-8. doi: 10.1111/j.1432-1033.1968.tb00357.x.
2
A stimulant to DNA synthesis in guinea-pig ear epidermis.豚鼠耳部表皮中DNA合成的刺激物。
Br J Dermatol. 1970 Dec;83(6):632-6. doi: 10.1111/j.1365-2133.1970.tb15757.x.
3
DNA synthesis in organ cultures of the hamster cheek pouch. Inhibition by a homologous extract.
仓鼠颊囊器官培养中的DNA合成。同源提取物的抑制作用。
Exp Cell Res. 1969 Dec;58(2):429-31. doi: 10.1016/0014-4827(69)90525-4.
4
Delayed inhibition of epidermal DNA synthesis after injection of an aqueous skin extract (chalone).注射皮肤水提取物(抑素)后表皮DNA合成的延迟抑制
Virchows Arch B Cell Pathol. 1969;4(1):45-53. doi: 10.1007/BF02906060.
5
A tissue-specific factor inhibiting DNA synthesis in mouse epidermis.
Natl Cancer Inst Monogr. 1973 Jul;38:79-90.
6
The epidermal chalone and keratinizing epithelia.表皮抑素与角质形成上皮
Natl Cancer Inst Monogr. 1973 Jul;38:61-8.
7
Experimental approach to the epidermal chalone.
Natl Cancer Inst Monogr. 1973 Jul;38:37-45.
8
Epidermal chalone. Effect on cell cycle and on development of hyperplasia.表皮抑素。对细胞周期及增生发展的影响。
Exp Cell Res. 1971 Jan;64(1):140-4. doi: 10.1016/0014-4827(71)90204-7.