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与一名特发性代偿性肝硬化患者腹泻相关的卡耶塔环孢子虫。

Cyclospora cayetanensis associated with diarrhea in a patient with idiopathic compensated hepatic cirrhosis.

作者信息

Yazar Süleyman, Yaman Ozan, Demirtaş Funda, Yalçin Saban, Yücesoy Mehmet, Sahin Izzet

机构信息

Erciyes University Medical Faculty, Department of Parasitology, Kayseri-Turkey.

出版信息

Acta Gastroenterol Belg. 2002 Oct-Dec;65(4):241-4.

Abstract

A 52 year-old male patient with idiopathic hepatic cirrhosis complaining of diarrhea and weakness was accepted to the gastroenterology clinic. In order to find out the causative etiologic agent of diarrhea, stool samples were examined by different methods and stained using modified Kinyoun's acid-fast stain. Following examination, approximately 9 microns diameter, acid-fast variable wrinkled spheres were seen and diagnosed as Cyclospora cayetanensis. Confirmation of the diagnosis was established by fluorescent microscope (380 to 420 nm excitation filter), which showed bright green to intense blue autofluorescent oocysts. It has been shown that, Cyclospora cayetanensis is a coccidian parasite mainly found in immunocompromised patients and that it may be the agent of prolonged diarrhea. Only three cyclosporiosis cases have been previously reported in our country; all three cases were AIDS patients. We report here a further case of Cyclospora cayetanensis infection in a patient with hepatic cirrhosis and we consider that this is the first case, which was reported in hepatic cirrhosis.

摘要

一名52岁患有特发性肝硬化的男性患者,因腹泻和乏力前往胃肠病诊所就诊。为了找出腹泻的病原体,对粪便样本采用不同方法进行检查,并使用改良金胺酚抗酸染色法进行染色。检查后,发现了直径约9微米、抗酸可变的皱缩球体,并诊断为卡耶塔环孢子球虫。通过荧光显微镜(380至420纳米激发滤光片)确诊,显示出亮绿色至深蓝色的自发荧光卵囊。研究表明,卡耶塔环孢子球虫是一种主要在免疫功能低下患者中发现的球虫寄生虫,可能是导致长期腹泻的病原体。我国此前仅报告过3例环孢子虫病病例;所有3例均为艾滋病患者。我们在此报告1例肝硬化患者感染卡耶塔环孢子球虫的病例,并认为这是首次报告的肝硬化患者感染该病原体的病例。

引用本文的文献

1
Epidemiology of Cyclospora Species in Humans in Malatya Province in Turkey.
Jundishapur J Microbiol. 2015 Jul 27;8(7):e18661. doi: 10.5812/jjm.18661v2. eCollection 2015 Jul.
2
Clinical significance of enteric protozoa in the immunosuppressed human population.
Clin Microbiol Rev. 2009 Oct;22(4):634-50. doi: 10.1128/CMR.00017-09.
3
Human cyclosporiosis in Turkey.
World J Gastroenterol. 2004 Jun 15;10(12):1844-7. doi: 10.3748/wjg.v10.i12.1844.

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