Saseen Joseph J
Department of Clinical Pharmacy, University of Colorado Health Sciences Center, Denver, USA.
J Fam Pract. 2003 Mar;52(3):192, 194.
Mortality with atrial fibrillation is similar with rhythm control and rate control treatment. However, adverse drug events and hospitalizations are more frequent with rhythm control therapy. Rate control therapy for atrial fibrillation should be the primary treatment strategy for an older high-risk population, but should not be extrapolated to younger and healthier patients (eg, patients with lone atrial fibrillation). These findings are consistent with another smaller study of patients with recurrent persistent atrial fibrillation.
房颤患者采用节律控制和心率控制治疗的死亡率相似。然而，节律控制治疗的药物不良事件和住院情况更为频繁。房颤的心率控制治疗应作为老年高危人群的主要治疗策略，但不应推广至年轻且健康的患者（如孤立性房颤患者）。这些发现与另一项针对复发性持续性房颤患者的规模较小的研究结果一致。
