Munts A G, Wennekes M J, Koehler P J
Atrium Medisch Centrum, afd. Neurologie, Postbus 4446, 6401 CX Heerlen.
Ned Tijdschr Geneeskd. 2003 Feb 8;147(6):257-60.
An 11-year-old girl with Sydenham chorea presented with a rapid onset of serious restlessness of mainly the right side of the body. Additional laboratory investigations revealed no abnormalities, yet this is not unusual for such cases. Valproic acid and pimozide were then successively prescribed because of the chorea. For secondary prevention she received long-term oral penicillin. Sydenham chorea is a manifestation of rheumatic fever and occurs after a throat infection by group A streptococci. The disease is characteristic and consists of a combination of choreic movements, hypotonia and emotional lability. The clinical course is diverse. Improvement usually occurs over a period of several months, although a significant proportion of patients exhibit little recovery.
一名患有 Sydenham 舞蹈病的 11 岁女孩出现身体右侧迅速发作的严重不安。进一步的实验室检查未发现异常，但这种情况在这类病例中并不罕见。由于舞蹈病，随后先后开了丙戊酸和匹莫齐特。为进行二级预防，她接受了长期口服青霉素治疗。Sydenham 舞蹈病是风湿热的一种表现，发生在 A 组链球菌引起的咽喉感染之后。该疾病具有特征性，由舞蹈样动作、肌张力减退和情绪不稳定组合而成。临床病程多样。通常在几个月内会有所改善，尽管相当一部分患者恢复甚微。
