基于磁珠文库的离子提取阶梯测序。
Ion-extraction ladder sequencing from bead-based libraries.
作者信息
Pastor Jose J, Lingard Iain, Bhalay Gurdip, Bradley Mark
机构信息
Departament de Química Orgànica, Universitat de Barcelona, Martí i Franquès, 1-11, 08028 Barcelona, Spain.
出版信息
J Comb Chem. 2003 Mar-Apr;5(2):85-90. doi: 10.1021/cc0200437.
PMID:12625697
Abstract
Ion-extraction mass spectrometry of ladders of mixtures of isotopically labeled compounds from single beads allows the unambiguous sequencing of bead-based peptides and offers significant advantages over traditional methods of library analysis.
摘要
对来自单个珠子的同位素标记化合物混合物阶梯进行离子提取质谱分析，能够对基于珠子的肽段进行明确测序，并且相较于传统的文库分析方法具有显著优势。
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