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锝-99m-葡庚糖酸盐作为一种脑扫描剂:与高锝酸盐的关键比较。

Technetium-99m-glucoheptonate as a brain-scanning agent: critical comparison with pertechnetate.

作者信息

Waxman A D, Tanacescu D, Siemsen J K, Wolfstein R S

出版信息

J Nucl Med. 1976 May;17(5):345-8.

PMID:1262934
Abstract

Delayed 99mTc-glucoheptonate and pertechnetate scans were evaluated in a paired study for their ability to detect brain lesions. Glucoheptonate was found to be superior in eight of 17 cases of brain tumor and in two of ten patients with cerebral infarction. In addition, early (30 min) 99mTc-glucoheptonate brain scans were compared with delayed studies: the former were inferior in 48% of the cases. We conclude that 99mTc-glucoheptonate is a promising agent for delayed brain scanning, offering better lesion detection than pertechnetate.

摘要

在一项配对研究中,对延迟的99m锝葡庚糖酸盐和高锝酸盐扫描检测脑病变的能力进行了评估。在17例脑肿瘤病例中有8例以及10例脑梗死患者中有2例发现葡庚糖酸盐表现更优。此外,还对早期(30分钟)的99m锝葡庚糖酸盐脑扫描与延迟扫描进行了比较:前者在48%的病例中表现较差。我们得出结论,99m锝葡庚糖酸盐是一种用于延迟脑扫描的有前景的药物,与高锝酸盐相比,它能更好地检测病变。

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引用本文的文献

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Evaluation of Technetium-99m glucoheptonate single photon emission computed tomography for brain tumor grading.锝-99m葡庚糖酸盐单光子发射计算机断层扫描用于脑肿瘤分级的评估
Asian J Neurosurg. 2016 Apr-Jun;11(2):118-28. doi: 10.4103/1793-5482.177633.
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Use of 99m-technetium-glucoheptonate as a tracer for brain tumor imaging: An overview of its strengths and pitfalls.使用锝-99m-葡庚糖酸盐作为脑肿瘤成像的示踪剂:其优势与不足概述。
Indian J Nucl Med. 2015 Jan-Mar;30(1):1-8. doi: 10.4103/0972-3919.147525.
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Neoplasm localization with radionuclides.
放射性核素肿瘤定位
Eur J Nucl Med. 1979 Oct;4(5):313-24. doi: 10.1007/BF00263297.