Diekmann F, Diekmann S, Taupitz M, Bick U, Winzer K-J, Hüttner C, Muller S, Jeunehomme F, Hamm B
Institut für Radiologie, Charité Berlin.
Rofo. 2003 Mar;175(3):342-5. doi: 10.1055/s-2003-37828.
To investigate the use of iodine-based contrast media in digital full-field mammography.
After performing initial phantom studies, seven patients underwent digital mammography (Senographe 2000D, GE Medical Systems, Milwaukee, USA) using a specially filtered beam before as well as 60, 120, and 180 seconds after injection of 80 ml of iodine contrast medium (Ultravist 370, Schering AG, Germany). The precontrast mammograms were then subtracted from the postcontrast mammograms and the resulting images compared with a contrast-enhanced dynamic MRI study, performed on all women.
Contrast medium accumulation within the tumors was visualized with a good quality in all cases. The conditions under which successful contrast-enhanced digital mammography can be performed were determined in phantom studies.
Contrast-enhanced digital mammography has a potential for improving the visualization of breast tumors in mammography using special beam filtering, adjusted x-ray parameters, proper timing, and suitable subtraction software.
研究碘对比剂在数字全视野乳腺摄影中的应用。
在进行初步体模研究后,7例患者在注射80ml碘对比剂(优维显370,德国先灵公司)前以及注射后60、120和180秒,使用特殊滤过射线束进行数字乳腺摄影(Senographe 2000D,美国通用电气医疗系统公司,密尔沃基)。然后将注射对比剂前的乳腺摄影图像从注射对比剂后的图像中减去,并将所得图像与所有女性均进行的对比增强动态磁共振成像研究结果进行比较。
所有病例中肿瘤内对比剂聚集均清晰可见。在体模研究中确定了成功进行对比增强数字乳腺摄影的条件。
使用特殊射线束滤过、调整X线参数、合适的时间以及合适的减影软件,对比增强数字乳腺摄影有潜力改善乳腺摄影中乳腺肿瘤的可视化。