Grant Jon E, Kim Suck Won, Potenza Marc N
Department of Psychiatry, University of Minnesota School of Medicine, 2450 Riverside Avenue, Minneapolis, MN 55454-1495, USA.
J Gambl Stud. 2003 Spring;19(1):85-109. doi: 10.1023/a:1021227214142.
In the present paper we discuss the current status of drug treatment for pathological gambling and the scientific rationales underlying the various pharmacological approaches. Specifically, we summarize the treatment study results of serotonin reuptake inhibitors, mood stabilizers, opioid antagonists, and atypical antipsychotics in pathological gambling. We also discuss dosage strategies, the duration of treatment, issues surrounding medication compliance, and approaches to treatment-refractory pathological gambling, such as pharmacological and behavioral augmentation.
在本文中，我们讨论了病理性赌博药物治疗的现状以及各种药理学方法背后的科学原理。具体而言，我们总结了5-羟色胺再摄取抑制剂、心境稳定剂、阿片类拮抗剂及非典型抗精神病药物在病理性赌博中的治疗研究结果。我们还讨论了用药策略、治疗持续时间、围绕药物依从性的问题以及难治性病理性赌博的治疗方法，如药物和行为强化。
