Budde W M, Jonas J B, Hayler J K, Mardin C Y
Department of Ophthalmology, Friedrich-Alexander Universität Erlangen-Nürnberg, Erlangen, Germany.
Eur J Ophthalmol. 2003 Jan-Feb;13(1):42-8. doi: 10.1177/112067210301300106.
To assess whether confocal scanning laser tomography of the optic disc and clinical ophthalmoscopy using stereoscopic optic disc photographs, agree in the evaluation of the deepest part of the optic cup.
The study included 33 eyes of patients with focal normal-pressure glaucoma. Using 15 degrees color stereoscopic optic disc photographs and dividing the optic disc into an upper and a lower half, two trained observers independently established the location of the deepest part of the cup. By selection, the two observers had made congruent judgements for all eyes in the study. All patients also underwent confocal scanning laser tomography of the optic disc using the Heidelberg Retina Tomograph (HRT). The location of the deepest "mean cup depth" was noted.
The deepest optic cup region based on stereoscopic evaluation of photographs and on scanning laser tomography did not correlate significantly with each other (p=0.18; chi-square test, linear-by-linear association). According to the scanning laser tomography data, the maximal optic cup depths were not correlated with the corresponding locations of maximal visual field defect (p=0.80). Using the stereo photographic data, the locations of maximal optic cup depth and maximal visual field defect were correlated (p=0.006).
In some glaucomatous eyes, confocal scanning laser tomographic assessment of the location of the deepest optic cup region does not agree with clinical judgement and, in contrast to clinical examination, does not correlate with the location of the maximal visual field defect.
评估视盘共焦扫描激光断层扫描与使用立体视盘照片的临床检眼镜检查在评估视杯最深部位时是否一致。
该研究纳入了33例局部正常眼压性青光眼患者的眼睛。使用15度彩色立体视盘照片并将视盘分为上半部分和下半部分,两名经过培训的观察者独立确定视杯最深部位的位置。经挑选,两名观察者对研究中的所有眼睛都做出了一致的判断。所有患者还使用海德堡视网膜断层扫描仪(HRT)对视盘进行了共焦扫描激光断层扫描。记录最深“平均杯深”的位置。
基于照片的立体评估和扫描激光断层扫描得出的最深视杯区域彼此之间无显著相关性(p = 0.18;卡方检验,线性-线性关联)。根据扫描激光断层扫描数据,最大视杯深度与相应最大视野缺损的位置无相关性(p = 0.80)。使用立体摄影数据时,最大视杯深度和最大视野缺损的位置具有相关性(p = 0.006)。
在一些青光眼眼中,对视杯最深区域位置的共焦扫描激光断层扫描评估与临床判断不一致,并且与临床检查不同,它与最大视野缺损的位置无相关性。