Chilla R, Arglebe C
MMW Munch Med Wochenschr. 1975 Sep 5;117(36):1425-8.
The secretion mechanism of the large salivary glands at the level of the acinus cells is presented to explain the side effects "dryness of the mouth and initial parotid pain on chewing". The importance of adrenergic alpha- and beta-receptors and a cholinergic receptor in the acinus cell membrane is discussed in connection with the action of antihypertensives on the autonomic nervous system. Experiments on rat salivary glands after treatment with clonidine, guanoxan and propranolol serve as a basis for this.
本文介绍了腺泡细胞水平上大唾液腺的分泌机制，以解释“口干和咀嚼时腮腺初发性疼痛”等副作用。结合抗高血压药物对自主神经系统的作用，讨论了腺泡细胞膜上肾上腺素能α和β受体以及胆碱能受体的重要性。以可乐定、胍生和普萘洛尔处理大鼠唾液腺后的实验作为此研究的基础。
