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传统冠状动脉旁路移植术和非体外循环冠状动脉旁路移植术后的心房颤动:心房颤动发生时间的两种相反趋势?

Atrial fibrillation after conventional and off-pump coronary artery bypass grafting: two opposite trends in timing of atrial fibrillation occurrence?

作者信息

Siebert Janusz, Lewicki Łukasz, Młodnicki Maciej, Rogowski Jan, Lango Romuald, Anisimowicz Lech, Narkiewicz Mirosława

机构信息

Department of Cardiac Surgery and Cardiology, Institute of Cardiology, Medical University, Gdańsk, Poland.

出版信息

Med Sci Monit. 2003 Mar;9(3):CR137-41.

PMID:12640343
Abstract

BACKGROUND

Atrial fibrillation (AF) is one of the most common complications after cardiac surgery. It occurs most often between the 2nd and 3rd postoperative day. The aim of this study was to compare the daily distribution of AF incidence between patients operated on with the standard coronary artery bypass grafting (CABG) technique and off-pump coronary artery bypass grafting on the beating heart (OPCABG) without extracorporeal circulation.

MATERIAL/METHODS: This was a prospective analysis of 1067 patients with coronary artery disease (CAD) operated on at our institute. 891 patients underwent CABG and 176 subjects were operated on by beating heart surgery using the OPCABG technique. Heart rhythm was analyzed continuously, and additionally a standard 12-lead ECG was performed once a day and continually in the case of clinical manifestations of arrhythmia. The observation period included 7 postoperative days (POD).

RESULTS

164 patients in the CABG group (18.43%) developed AF compared with 28 (16%) in the OPCABG group (OR=1.18; 95% CI (0.75-1.85); p=0.451). The peak of AF incidence in the CABG group appeared on the 2nd POD, while in contrast the peak of AF incidence after OPCABG was observed on the 1st POD.

CONCLUSIONS

We found no statistically significant difference in AF incidence after CABG and OPCABG. Different trends were noticed in the timing of occurrence of AF in these two groups.

摘要

背景

心房颤动(AF)是心脏手术后最常见的并发症之一。它最常发生在术后第2天至第3天之间。本研究的目的是比较采用标准冠状动脉旁路移植术(CABG)技术进行手术的患者与在非体外循环下进行心脏不停跳冠状动脉旁路移植术(OPCABG)的患者之间房颤发生率的每日分布情况。

材料/方法:这是对在我们研究所接受手术的1067例冠心病(CAD)患者进行的前瞻性分析。891例患者接受了CABG手术,176例患者采用OPCABG技术进行了心脏不停跳手术。持续分析心律,此外,每天进行一次标准12导联心电图检查,若出现心律失常临床表现则持续进行检查。观察期包括术后7天(POD)。

结果

CABG组有164例患者(18.43%)发生房颤,而OPCABG组有28例患者(16%)发生房颤(OR = 1.18;95%CI(0.75 - 1.85);p = 0.451)。CABG组房颤发生率的峰值出现在术后第2天,而相比之下,OPCABG术后房颤发生率的峰值出现在术后第1天。

结论

我们发现CABG和OPCABG术后房颤发生率在统计学上无显著差异。在这两组中,房颤发生的时间出现了不同的趋势。

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1
Atrial fibrillation after conventional and off-pump coronary artery bypass grafting: two opposite trends in timing of atrial fibrillation occurrence?传统冠状动脉旁路移植术和非体外循环冠状动脉旁路移植术后的心房颤动:心房颤动发生时间的两种相反趋势?
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[Influence of cardiopulmonary bypass on risk of AF after coronary artery bypass grafting].[体外循环对冠状动脉旁路移植术后房颤风险的影响]
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Cardioplegic arrest does not increase the risk of atrial fibrillation after coronary artery bypass surgery.心脏停搏并不会增加冠状动脉旁路移植术后房颤的风险。
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Reduced atrial fibrillation in patients immediately extubated after off-pump coronary artery bypass grafting.非体外循环冠状动脉搭桥术后立即拔管患者的房颤发生率降低。
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Relation of inflammatory cytokines to atrial fibrillation after off-pump coronary artery bypass grafting.非体外循环冠状动脉搭桥术后炎症细胞因子与心房颤动的关系
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2
Clinical Effect and Prognosis of Off-Pump Minimally Invasive Direct Coronary Artery Bypass.非体外循环微创直接冠状动脉旁路移植术的临床疗效与预后
Med Sci Monit. 2017 Mar 3;23:1123-1128. doi: 10.12659/msm.902940.
3
Post-operative atrial fibrillation: a maze of mechanisms.
术后心房颤动:错综复杂的机制。
Europace. 2012 Feb;14(2):159-74. doi: 10.1093/europace/eur208. Epub 2011 Aug 6.
4
Predictors of atrial fibrillation following coronary artery bypass surgery.冠状动脉旁路手术后心房颤动的预测因素。
Med Sci Monit. 2011 Jan;17(1):CR48-55. doi: 10.12659/msm.881329.