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[胰腺胰岛素瘤——影像学诊断的难点]

[Insulinoma of the pancreas--difficulties with imaging].

作者信息

Owecki Maciej, Waśko Ryszard, Horst-Sikorska Wanda, Drews Michał, Stawny Bolesław, Sowiński Jerzy

机构信息

Katedra i Klinika Endokrynologii i Przemiany Materii AM w Poznaniu.

出版信息

Pol Arch Med Wewn. 2002 Oct;108(4):983-6.

Abstract

We present a case of 29-year old man in whom despite the lack of finding tumor in USG and CT surgical intervention was performed and insulinoma of the pancreas was excised. Insulinoma was diagnosed on the basis of clinical picture (Whipple's triade) that was reassured by positive fast test. The fast was terminated at 11 and half hours because of neuroglycopenic symptoms with serum glucose and insulin levels 2.0 mmol/l (36 mg/dl) and 11.07 microU/ml respectively, which established the diagnosis. Laparotomy was performed, during which the tumor was palpated and seen in ultrasonography in the head of pancreas. The tumor of 12 mm diameter was excised. Histopathological examination revealed benign insulinoma. After surgery the symptoms alleviated completely. The patient with proper glucose levels was discharged in good health. The case supports high usefulness of intraoperative ultrasonography and surgeon's palpation.

摘要

我们报告一例29岁男性患者,尽管超声检查(USG)和计算机断层扫描(CT)未发现肿瘤,但仍进行了手术干预,并切除了胰腺胰岛素瘤。胰岛素瘤是根据临床表现(惠普尔三联征)诊断的,快速血糖检测呈阳性进一步证实了诊断。禁食11个半小时后,因出现神经低血糖症状而终止,当时血清葡萄糖和胰岛素水平分别为2.0 mmol/L(36 mg/dl)和11.07 μU/ml,由此确立了诊断。进行了剖腹手术,术中通过触诊发现胰腺头部有肿瘤,超声检查也可见该肿瘤。切除了直径为12 mm的肿瘤。组织病理学检查显示为良性胰岛素瘤。术后症状完全缓解。血糖水平正常的患者健康出院。该病例支持术中超声检查和外科医生触诊的高度实用性。

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