Perkins Bruce A, Bril Vera
Toronto General Hospital, University Health Network, 200 Elizabeth Street, Toronto, Ontario M5G 2C4, Canada.
Curr Diab Rep. 2002 Dec;2(6):495-500. doi: 10.1007/s11892-002-0119-x.
Diabetic sensorimotor polyneuropathy (DSP) remains the most common microvascular complication of both type I and type 2 diabetes, and poses a unique set of management challenges in the prevention of foot complications. Although different quantitative tests are available, the preliminary diagnosis of DSP can be reliably made using simple and rapid screening tests in the family physician's office or in the diabetes clinic. The Semmes-Weinstein 10-g monofilament examination is a popular, simple clinical modality for the prediction of early DSP, foot ulceration, and amputation, and, in turn, a predictor of mortality in patients with diabetes. The management of DSP is centered on optimal glycemic control, diligent foot care, and pain control as a means of preventing the progression of DSP and reducing the morbidity associated with foot complications.
糖尿病性感觉运动性多发性神经病变（DSP）仍然是1型和2型糖尿病最常见的微血管并发症，在预防足部并发症方面带来了一系列独特的管理挑战。尽管有不同的定量检测方法，但在家庭医生办公室或糖尿病诊所，使用简单快速的筛查测试就能可靠地对DSP进行初步诊断。Semmes-Weinstein 10克单丝检查是一种常用的、简单的临床方法，用于预测早期DSP、足部溃疡和截肢，进而预测糖尿病患者的死亡率。DSP的管理以优化血糖控制、精心足部护理和疼痛控制为中心，以此预防DSP进展并降低与足部并发症相关的发病率。
