Lee Timothy C, Barshes Neal R, Agee Erin E, O'Mahoney Christine A, Brunicardi F Charles, Goss John A
Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX 77030, USA.
Curr Diab Rep. 2006 Aug;6(4):323-7. doi: 10.1007/s11892-006-0068-x.
Diabetes mellitus is a leading cause of morbidity and mortality in the Western world. Currently, the only forms of beta-cell replacement are whole organ pancreas transplantation and pancreatic islet transplantation. Whole organ transplantation has demonstrated benefits in prevention and reversal of diabetic complications with sustainable long-term outcomes. Pancreatic islet transplantation continues to be a field that needs further study to ascertain the true benefit of islet transplantation for diabetic complications. This can only be achieved with improvement in long-term islet allograft survival.
糖尿病是西方世界发病和死亡的主要原因。目前，β细胞替代的唯一形式是全器官胰腺移植和胰岛移植。全器官移植已在预防和逆转糖尿病并发症方面显示出益处，并具有可持续的长期效果。胰岛移植仍是一个需要进一步研究的领域，以确定胰岛移植对糖尿病并发症的真正益处。这只有通过提高胰岛同种异体移植的长期存活率才能实现。
