López Javier, Rivera Marisol, Concha Juan Carlos, Gatica Silvana, Loeffeholz Mike, Barriga Omar
Clinica Veterinaria Alcántara, Puente Alto, Santiago, Chile.
Rev Med Chil. 2003 Jan;131(1):67-70.
Ehrlichiosis is a non contagious infectious disease, mainly transmitted by thick bites. In 1998, this infection was detected in dogs, for the first time, in Chile.
To establish if there is human exposure to Ehrlichia sp in Chile.
Blood samples from 17 dogs with ehrlichiosis and 19 humans who had contact with them were studied to determine human exposure to Ehrlichia equi and Ehrlichia chaffeensis in Chile. Samples were analyzed by indirect immunofluorecence and by polymerase chain reaction (PCR).
Six dogs had positive titers against both species of ehrlichia; 2 with titers of 1/256; 3 with titers over 1/512 to Ehrlichia equi and titers of 1/256, 1/128 and 1/64 to Ehrlichia chaffeensis respectively, and 1 with titers of 1/256 to Ehrlichia equi and titers of 1/128 to Ehrlichia chaffeensis. Two of the 19 humans, had positive titers against both antigens (1/128). PCR reactions were negative in both human and canine sera.
These results confirm that human exposure to Ehrlichia sp. Epidemiological surveillance for human ehrlichiosis should be implemented in the country.
埃立克体病是一种非传染性传染病,主要通过硬蜱叮咬传播。1998年,智利首次在犬类中检测到这种感染。
确定智利是否存在人类暴露于埃立克体属的情况。
研究了17只患有埃立克体病的犬的血液样本以及19名与它们有接触史的人的血液样本,以确定智利人类暴露于马埃立克体和查菲埃立克体的情况。通过间接免疫荧光法和聚合酶链反应(PCR)对样本进行分析。
6只犬对两种埃立克体的滴度均为阳性;2只犬对马埃立克体的滴度为1/256,对查菲埃立克体的滴度分别为1/512以上、1/256、1/128和1/64;1只犬对马埃立克体的滴度为1/256,对查菲埃立克体的滴度为1/128。19名人类中有2人对两种抗原的滴度均为阳性(1/128)。人类和犬类血清的PCR反应均为阴性。
这些结果证实人类暴露于埃立克体属。该国应开展人类埃立克体病的流行病学监测。