Brady Rebecca C, Bissler John J
Department of Pediatrics, Division of Nephrology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Pediatr Nephrol. 2003 Mar;18(3):293-6. doi: 10.1007/s00467-002-1055-3. Epub 2003 Feb 12.
Severe illness with acute renal failure, leukopenia, thrombocytopenia, and coagulopathy frequently occurs with hemolytic uremic syndrome/thrombotic thrombocytopenic purpura, hematological malignancies, sepsis, and collagen-vascular diseases. We present a 16-year-old male fast-food worker with underlying chronic renal insufficiency who manifested these abnormalities as a result of Ehrlichia chaffeensis sepsis. Doxycycline therapy and aggressive supportive care led to complete recovery.