Villavicencio Mavrich H
Servicio de Urología, Fundación Puigvert, Barcelona.
Actas Urol Esp. 2002 Nov-Dec;26(10):759-62. doi: 10.1016/s0210-4806(02)72854-4.
Breakthroughs seen over recent years in the management of testicle germ cell tumours have been very significant. The prognostic influence of such advances has proven to be crucial and translates the progressive opening of oncology to new fields and technologies. In his review, the author articulates a potential target in the management of these germ cells tumours to further increase survival rates. The therapeutic challenges include the consideration of prognostic factors, decreased toxicity of established therapies, addition of new molecules to first line therapy and the recent application of molecular biology techniques to both diagnostic and therapeutic aspects.
近年来,睾丸生殖细胞肿瘤的管理取得了非常显著的突破。这些进展对预后的影响已被证明至关重要,也意味着肿瘤学不断向新领域和新技术开放。在他的综述中,作者阐明了在这些生殖细胞肿瘤管理中的一个潜在靶点,以进一步提高生存率。治疗面临的挑战包括考虑预后因素、降低现有疗法的毒性、在一线治疗中添加新分子,以及最近分子生物学技术在诊断和治疗方面的应用。